A kicked in door and shattered glass covered the welcome mat at Margaret River's Priceline Pharmacy this morning.
An offender smashed the of the Bussell Highway store at 3.40am this morning a made off with various medication before fleeing.
Police believe the man fled in a vehicle, possibly a utility.
The store was closed this morning as staff swept up broken glass and arranged to have a new door installed.
The store has now resumed normal trading.
Police are investigating the incident and are asking for anyone who saw anything suspicious in the area to contact Crime Stoppers on 1800 333 000.
More as the story develops.